Is Dominant-Side Onset Associated With a Better Motor Compensation in Parkinson's Disease?
Identifieur interne : 000201 ( Main/Exploration ); précédent : 000200; suivant : 000202Is Dominant-Side Onset Associated With a Better Motor Compensation in Parkinson's Disease?
Auteurs : Jee H. Ham [Corée du Sud] ; Jae J. Lee [Corée du Sud] ; Jae S. Kim [Corée du Sud] ; Phil H. Lee [Corée du Sud] ; Young H. Sohn [Corée du Sud]Source :
- Movement disorders : official journal of the Movement Disorder Society [ 1531-8257 ] ; 2015.
Abstract
Unilateral onset and persistent asymmetry of motor signs are unique features of PD. The dominant hemisphere may have more efficient motor networks with greater neural reserve to cope with pathological changes. Therefore, this study compared dominant-side onset and non-dominant-side onset PD to evaluate whether dominant-side onset patients have greater neural reserve and fewer motor deficits despite similar pathological changes.
DOI: 10.1002/mds.26418
PubMed: 26408124
Affiliations:
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Ham</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Yonsei University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Lee, Jae J" sort="Lee, Jae J" uniqKey="Lee J" first="Jae J" last="Lee">Jae J. Lee</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Yonsei University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Kim, Jae S" sort="Kim, Jae S" uniqKey="Kim J" first="Jae S" last="Kim">Jae S. Kim</name><affiliation wicri:level="3"><nlm:affiliation>Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Lee, Phil H" sort="Lee, Phil H" uniqKey="Lee P" first="Phil H" last="Lee">Phil H. Lee</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Yonsei University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author><author><name sortKey="Sohn, Young H" sort="Sohn, Young H" uniqKey="Sohn Y" first="Young H" last="Sohn">Young H. Sohn</name><affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation><country xml:lang="fr">Corée du Sud</country><wicri:regionArea>Department of Neurology, Yonsei University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement></placeName></affiliation></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="eISSN">1531-8257</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Unilateral onset and persistent asymmetry of motor signs are unique features of PD. The dominant hemisphere may have more efficient motor networks with greater neural reserve to cope with pathological changes. Therefore, this study compared dominant-side onset and non-dominant-side onset PD to evaluate whether dominant-side onset patients have greater neural reserve and fewer motor deficits despite similar pathological changes.</div></front></TEI><affiliations><list><country><li>Corée du Sud</li></country><settlement><li>Séoul</li></settlement></list><tree><country name="Corée du Sud"><noRegion><name sortKey="Ham, Jee H" sort="Ham, Jee H" uniqKey="Ham J" first="Jee H" last="Ham">Jee H. Ham</name></noRegion><name sortKey="Kim, Jae S" sort="Kim, Jae S" uniqKey="Kim J" first="Jae S" last="Kim">Jae S. Kim</name><name sortKey="Lee, Jae J" sort="Lee, Jae J" uniqKey="Lee J" first="Jae J" last="Lee">Jae J. Lee</name><name sortKey="Lee, Phil H" sort="Lee, Phil H" uniqKey="Lee P" first="Phil H" last="Lee">Phil H. Lee</name><name sortKey="Sohn, Young H" sort="Sohn, Young H" uniqKey="Sohn Y" first="Young H" last="Sohn">Young H. 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